Tadafil

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Tadalafil

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Tadalafil INN 5 mg & 10 mg Tab
Anti-erectile Dysfunction Agent
Erectile Dysfunction
Benign Prostatic Hyperplasia
Erectile Dysfunction and Benign Prostatic Hyperplasia

Dosage and Administration:
Erectile Dysfunction
Tadafil for Use as Needed for Erectile Dysfunction:
The recommended starting dose of Tadafil for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity.
The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability. The maximum recommended dosing frequency is once per day in most patients.
Tadafil for Once Daily Use for Erectile Dysfunction:
The recommended starting dose of Tadafil for once daily use is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.
The Tadafil dose for once daily use may be increased to 5 mg, based on individual efficacy and tolerability.
Tadafil for Once Daily Use for Benign Prostatic Hyperplasia:
The recommended dose of Tadafil for once daily use is 5 mg, taken at approximately the same time every day.
Tadafil for Once Daily Use for Erectile Dysfunction and Benign Prostatic Hyperplasia:
The recommended dose of Tadafil for once daily use is 5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.
Renal Insufficiency:
For use as needed:
Mild (creatinine clearance 51 to 80 ml/min): No dose adjustment is required.
Moderate (creatinine clearance 31 to 50 ml/min): A starting dose of 5 mg not more than once per day is recommended and the maximum dose should be limited to 10 mg not more than once in every 48 hours.
Severe (creatinine clearance < 30 ml/min and on hemodialysis): The maximum recommended dose is 5 mg not more than once in every 72 hours.
For once daily use:
Mild (creatinine clearance 51 to 80 ml/min): No dose adjustment is required.
Moderate (creatinine clearance 31 to 50 ml/min): No dose adjustment is required.
Severe (creatinine clearance < 30 ml/min and on hemodialysis): Tadafil for once daily use is not recommended. Hepatic Impairment, For use as needed: Mild or moderate: The dose should not exceed 10 mg once per day. Severe: Not recommended. For once daily use: Mild or moderate: Tadalafil for once daily use has not been extensively evaluated in patients with hepatic insufficiency. Therefore, caution is advised if Tadalafil for once daily is prescribed to these patients. Severe: Not recommended. Geriatrics: No dose adjustment is required in patients>65 years of age.
Use with Food:
Tadafil may be taken without regard to food.
Presentation:
Tadafil 5 mg Tablet: Each box contains 1X4’s tablets in Alu-PVC blister pack.
Tadafil 10 mg Tablet: Each box contains 1X4’s tablets in Alu-PVC blister pack.

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